TNC Antibody
Product Specifications
Gene Name
Tenascin C
Gene Aliases
150-225; cytotactin; deafness, autosomal dominant 56; DFNA56; glioma-associated-extracellular matrix antigen; GMEM; GP; GP 150-225; Hexabrachion; hexabrachion (tenascin) ; HXB; JI; myotendinous antigen; neuronectin; tenascin; Tenascin-C; tenascin-C additional domain 1; TN; TN-C.
Gene ID
3371
Accession Number
NP_002151.2XP_005252029.1XP_005252031.1XP_005252032.1
Reactivity
Human
Immunogen
Protein preparation from a homogenate of a human mammary tumour specimen.
Target
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327) .
Clonality
Monoclonal
Clone
T2H5
Type
Monoclonal Antibody
Applications
Immunohistochemistry-Paraffin|Immunoprecipitation|Western blot
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Buffer
Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
The antibody T2H5 recognizes tenascin, a large hexameric extracellular matrix glycoprotein.
NCBI Gene Symbol
TNC
Host or Source
Mouse
Protein Name
Tenascin
Gene Name URL
TNC
CAS Number
9007-83-4
Nucleotide Accession Number
NM_002160.3XM_005251972.2XM_005251974.2XM_005251975.2
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