KRT18 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Keratin 18

Gene Aliases

Cell proliferation-inducing gene 46 protein; CK-18; CYK18; cytokeratin 18; Cytokeratin-18; K18; keratin 18, type I; keratin, type I cytoskeletal 18; Keratin-18.

Gene ID

3875

Accession Number

NP_000215.1NP_954657.1

Reactivity

Mammal

Immunogen

Cytoskeleton preparation of epidermal carcinoma cell line A431.

Target

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection.

Clonality

Monoclonal

Clone

C-04

Conjugation

Biotin

Type

Monoclonal Antibody

Applications

Purification

Purified by size-exclusion chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Buffer

Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Reconstitution

2°C to 8°C

Fragment

IgG1

Specificity

The antibody C-04 reacts with Cytokeratin 18 (45 kDa), a member of intermediate filaments subfamily represented in epithelial tissues.

NCBI Gene Symbol

KRT18

Host or Source

Mouse

Protein Name

Keratin, type I cytoskeletal 18

Gene Name URL

KRT18

Nucleotide Accession Number

NM_000224.2NM_199187.1

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