CD86 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
CD86 antigen
Gene Aliases
Activation B7-2 antigen; B7; B7.2; B70; B7-2; Cd28l; Cd28l2; CLS1; early T cell costimulatory molecule-1; Early T-cell costimulatory molecule 1; ETC-1; Ly5; Ly-5; Ly58; Ly-58; MB7; MB7-2; T-lymphocyte activation antigen CD86; TS/A-2.
Gene ID
12524
Accession Number
NP_001193853.1NP_001193854.1NP_008820.3NP_787058.4NP_795711.1
Reactivity
Mouse
Immunogen
LPS-activated CBA/Cs mouse splenic B cells
Target
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation.
Clonality
Monoclonal
Clone
GL-1
Type
Monoclonal Antibody
Applications
Flow cytometry|Immunocytochemistry|Immunohistochemistry-Frozen|Immunoprecipitation
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Reconstitution
2°C to 8°C
Fragment
IgG2a
Specificity
The rat monoclonal antibody GL-1 reacts with CD86 (B7-2), a 70-80 kDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
NCBI Gene Symbol
Cd86
Host or Source
Rat
Protein Name
T-lymphocyte activation antigen CD86
Gene Name URL
Cd86
Nucleotide Accession Number
NM_001206924.1NM_001206925.1NM_006889.4NM_175862.4NM_176892.1
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