SELP Antibody
Product Specifications
Gene Name
Selectin P
Gene Aliases
CD62; CD62 antigen-like family member P; CD62P; GMP140; GMP-140; granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; GRMP; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; P-selectin; selectin P (granule membrane protein 140kDa, antigen CD62) .
Gene ID
6403
Accession Number
NP_002996.2XP_005245492.1XP_005245493.1
Reactivity
Human
Immunogen
Human platelets
Target
Ca (2+) -dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
Clonality
Monoclonal
Clone
HI62P
Type
Monoclonal Antibody
Applications
Flow cytometry|Western blot
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
The antibody HI62P recognizes CD62P (P-selectin), a 140 kD single chain type I transmembrane glycoprotein present in secretory alpha-granules in platelets, in Weibel-Palade bodies in endothelial cells and in megakaryocytes; it is relocated to the plasma membrane upon activation.
NCBI Gene Symbol
SELP
Host or Source
Mouse
Protein Name
P-selectin
Gene Name URL
SELP
CAS Number
9007-83-4
Nucleotide Accession Number
NM_003005.3XM_005245435.1XM_005245436.2
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