CD55 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
CD55 molecule (Cromer blood group)
Gene Aliases
CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group) ; CHAPLE; complement decay-accelerating factor; CR; CROM; Cromer blood group antigen; DAF; Rh blood group D antigen; TC.
Gene ID
1604
Accession Number
NP_000565.1NP_001108224.1NP_001287832.1NP_001287833.1
Reactivity
Human|Non-human Primate
Immunogen
HPB-ALL human T cell line
Target
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274) . Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829) .
Clonality
Monoclonal
Clone
MEM-118
Conjugation
Biotin
Type
Monoclonal Antibody
Applications
Flow cytometry|Immunohistochemistry-Paraffin|Immunoprecipitation|Western blot
Purification
Purified by size-exclusion chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Buffer
Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
Reconstitution
2°C to 8°C
Fragment
IgM
Specificity
HLDA V; WS Code AS S016//
NCBI Gene Symbol
CD55
Host or Source
Mouse
Protein Name
Complement decay-accelerating factor
Gene Name URL
CD55
Nucleotide Accession Number
NM_000574.4NM_001114752.2NM_001300903.1NM_001300904.1
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