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SEMA7A Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Semaphorin 7A (John Milton Hagen blood group)

Gene Aliases

CD108; CDw108; H-SEMA-K1; H-Sema-L; JMH; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group) ; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema K1; sema L; SEMAK1; SEMAL; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) ; semaphorin-7A; semaphorin-K1; semaphorin-L.

Gene ID

8482

Accession Number

NP_001139501.1NP_001139502.1NP_003603.1

Reactivity

Human

Immunogen

HPB-ALL human T cell line

Target

Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.

Clonality

Monoclonal

Clone

MEM-150

Type

Monoclonal Antibody

Applications

Flow cytometry|Immunoprecipitation|Western blot

Purification

Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Buffer

Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0

Reconstitution

2°C to 8°C

Fragment

IgM

Specificity

HLDA V; WS Code AS S017 HLDA V; WS Code BP BP347 HLDA VI; WS Code BP 401 HLDA VI; WS Code BP 475 HLDA VI; WS Code NL N-L156 HLDA VI; WS Code P PR-65//

NCBI Gene Symbol

SEMA7A

Host or Source

Mouse

Protein Name

Semaphorin-7A

Gene Name URL

SEMA7A

Nucleotide Accession Number

NM_001146029.1NM_001146030.1NM_003612.3

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