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ARAP1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

Gene Aliases

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1; centaurin-delta-2; CENTD2; cnt-d2.

Gene ID

116985

Accession Number

NP_001035207.1NP_001128662.1NP_056057.2

Reactivity

Human

Immunogen

His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1

Target

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns (3,4,5) P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns (3,4,5) P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity) .

Clonality

Monoclonal

Clone

ARAP1-2

Type

Monoclonal Antibody

Applications

Immunocytochemistry|Immunoprecipitation|Western blot

Purification

Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Buffer

Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Reconstitution

2°C to 8°C

Fragment

IgG1

Specificity

The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein.

NCBI Gene Symbol

ARAP1

Host or Source

Mouse

Protein Name

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

Gene Name URL

ARAP1

Nucleotide Accession Number

NM_001040118.2NM_001135190.1NM_015242.4

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