Anti-DCC (human) (Axel-1) Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
DCC netrin 1 receptor
Gene Aliases
Colorectal cancer suppressor; CRC18; CRCR1; deleted in colorectal carcinoma; HGPPS2; IGDCC1; immunoglobulin superfamily DCC subclass member 1; MRMV1; netrin receptor DCC; NTN1R1; putative colorectal tumor suppressor; tumor suppressor protein DCC.
Gene ID
1630
Reactivity
Human
Immunogen
Recombinant human DCC fibronectin domain 5 (Prod. No. ALX-522-109) .
Target
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Clonality
Monoclonal
Clone
Axel-1
Type
Monoclonal Antibody
Source
Purified from concentrated hybridoma tissue culture supernatant.
Applications
Flow cytometry|Functional assay
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
Long Term Storage : //-20C
Short Term Storage : //+4C
Handling : //Avoid freeze/thaw cycles.
Stable for at least 1 year after receipt when stored at -20C.Short Term Storage : //+4C
Handling : //Avoid freeze/thaw cycles.
Stable for at least 1 year after receipt when stored at -20C.Handling : //Avoid freeze/thaw cycles.
Stable for at least 1 year after receipt when stored at -20C.
Fragment
IgG2a &lambda
Specificity
Recognizes human DCC.
NCBI Gene Symbol
DCC
Host or Source
Mouse
Protein Name
Netrin receptor DCC
Gene Name URL
DCC
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