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Anti-TWEAK (human) (Mira-2) Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

TNF superfamily member 12|TNFSF12-TNFSF13 readthrough

Gene Aliases

APO3 ligand; APO3/DR3 ligand; APO3L; DR3LG; TNF-related WEAK inducer of apoptosis; TNFSF12-TNFSF13 protein; TNLG4A; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor (ligand) superfamily, member 12-member 13; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; tumor necrosis factor superfamily member 12; TWEAK; TWE-PRIL.

Gene ID

407977|8742

Reactivity

Human

Immunogen

Recombinant human TWEAK extracellular domain (aa 106-249) (Prod. No. ALX-522-021) .

Target

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Clonality

Monoclonal

Clone

Mira-2

Type

Monoclonal Antibody

Source

Purified from concentrated hybridoma tissue culture supernatant.

Applications

Enzyme-linked immunosorbent assay|Flow cytometry|Immunoprecipitation

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1mg/ml

Reconstitution

Long Term Storage : //-20C Short Term Storage : //+4C Handling : //After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles Stable for at least 1 year after receipt when stored at -20C.Short Term Storage : //+4C Handling : //After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles Stable for at least 1 year after receipt when stored at -20C.Handling : //After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles Stable for at least 1 year after receipt when stored at -20C.

Fragment

IgG1

Specificity

Recognizes human TWEAK.

NCBI Gene Symbol

TNFSF12|TNFSF12-TNFSF13

Host or Source

Mouse

Protein Name

Tumor necrosis factor ligand superfamily member 12

Gene Name URL

TNFSF12|TNFSF12-TNFSF13

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