IL33 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 33
Gene Aliases
C9orf26; DVS27; DVS27-related protein; IL1F11; interleukin-1 family member 11; interleukin-33; NFEHEV; NF-HEV; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules.
Gene ID
90865
Accession Number
NP_001186569.1NP_001186570.1NP_254274.1XP_005251683.1XP_005251684.1
Reactivity
Human|Mouse|Rat
Immunogen
Recombinant human IL-33 (aa 112-270)
Target
Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016) . Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528) .
Clonality
Monoclonal
Clone
Nessy-1
Conjugation
Unconjugated
Type
Monoclonal Antibody
Source
Purified from ascites.
Applications
Enzyme-linked immunosorbent assay|Immunoprecipitation|Western blot
Purification
Protein G-affinity purified.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid// PBS
Reconstitution
Store short-term at 4° C; long-term at -20° C. Stable for at least one year after receipt when stored at -20° C.
Fragment
IgG1k
Specificity
Recognizes human, mouse and rat pro-IL-33 (precursor) and mature IL-33.
NCBI Gene Symbol
IL33
Host or Source
Mouse
Protein Name
Interleukin-33
Gene Name URL
IL33
Nucleotide Accession Number
NM_001199640.1NM_001199641.1NM_033439.3XM_005251626.3XM_005251627.1
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