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PRF1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Perforin 1 (pore forming protein)

Gene Aliases

Cytolysin; lymphocyte pore-forming protein; P; P1; pe; perforin-1; Pfn; Pfp; pore forming protein; Prf; Prf-1.

Gene ID

18646

Accession Number

NP_001076585.1NP_005032.2

Reactivity

Human|Mouse

Immunogen

Recombinant mouse perforin (aa 98-534) .

Target

Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Clonality

Monoclonal

Clone

CE2.10

Type

Monoclonal Antibody

Applications

Immunoprecipitation|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1mg/ml

Reconstitution

Long Term Storage : //+4C Handling : //Do not freeze/thaw. Stable for at least 6 months after receipt when stored undiluted at +4C.Handling : //Do not freeze/thaw. Stable for at least 6 months after receipt when stored undiluted at +4C.

Fragment

IgG2a

Specificity

Recognizes an epitope in the region aa 402-534 of human and mouse perforin.

NCBI Gene Symbol

Prf1

Host or Source

Mouse

Protein Name

Perforin-1

Gene Name URL

Prf1

Nucleotide Accession Number

NM_001083116.1NM_005041.4

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