Anti-FasL (mouse) (H11) Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Fas ligand (TNF superfamily, member 6)
Gene Aliases
APT1; APT1LG1; CD178; CD95; CD95 ligand; CD95L; CD95-L; F; Fa; Fas antigen ligand; Fas-L; Faslg; generalized lymphoproliferative disease; gld; Tnfs; Tnfsf6; Tnlg1a; tumor necrosis factor ligand 1a; tumor necrosis factor ligand superfamily member 6.
Gene ID
14103
Reactivity
Mouse
Immunogen
Synthetic peptide corresponding to aa 196-220 of mouse FasL (CD95L; APO-1L; CD178) .
Target
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:7511063) . Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:19794494, PubMed:7532682) . Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (PubMed:19794494) . TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (PubMed:10779162) . Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (By similarity) .
Clonality
Monoclonal
Clone
H11
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
Flow cytometry|Immunocytochemistry|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
Long Term Storage : //+4C
Handling : //Do not freeze/thaw.
Stable for at least 6 months after receipt when stored at +4C undiluted.Handling : //Do not freeze/thaw.
Stable for at least 6 months after receipt when stored at +4C undiluted.
Fragment
IgG2a
Specificity
Recognizes mouse FasL.
NCBI Gene Symbol
Fasl
Host or Source
Rat
Protein Name
Tumor necrosis factor ligand superfamily member 6
Gene Name URL
Fasl
Frequently Asked Questions
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