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Anti-FasL (mouse) (H11) Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Fas ligand (TNF superfamily, member 6)

Gene Aliases

APT1; APT1LG1; CD178; CD95; CD95 ligand; CD95L; CD95-L; F; Fa; Fas antigen ligand; Fas-L; Faslg; generalized lymphoproliferative disease; gld; Tnfs; Tnfsf6; Tnlg1a; tumor necrosis factor ligand 1a; tumor necrosis factor ligand superfamily member 6.

Gene ID

14103

Reactivity

Mouse

Immunogen

Synthetic peptide corresponding to aa 196-220 of mouse FasL (CD95L; APO-1L; CD178) .

Target

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:7511063) . Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:19794494, PubMed:7532682) . Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (PubMed:19794494) . TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (PubMed:10779162) . Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (By similarity) .

Clonality

Monoclonal

Clone

H11

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

Flow cytometry|Immunocytochemistry|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1mg/ml

Reconstitution

Long Term Storage : //+4C Handling : //Do not freeze/thaw. Stable for at least 6 months after receipt when stored at +4C undiluted.Handling : //Do not freeze/thaw. Stable for at least 6 months after receipt when stored at +4C undiluted.

Fragment

IgG2a

Specificity

Recognizes mouse FasL.

NCBI Gene Symbol

Fasl

Host or Source

Rat

Protein Name

Tumor necrosis factor ligand superfamily member 6

Gene Name URL

Fasl

Frequently Asked Questions

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