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THP-PEG6-OH

Product Specifications

UNSPSC Description

THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

Target Antigen

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related;PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/thp-peg6-oh.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

OCCOCCOCCOCCOCCOCCOC1CCCCO1

Molecular Weight

366.45

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.|[2]Masahiro Tomita, et al. Antibody specifically recognizing resin plasticizer compound. WO2005105846A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-126918/THP-PEG6-OH-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-126918/

Clinical Information

No Development Reported

CAS Number

42607-87-4

Available Sizes

Curated Selection

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