THP-PEG6-OH
Product Specifications
UNSPSC Description
THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thp-peg6-oh.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
OCCOCCOCCOCCOCCOCCOC1CCCCO1
Molecular Weight
366.45
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.|[2]Masahiro Tomita, et al. Antibody specifically recognizing resin plasticizer compound. WO2005105846A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126918/THP-PEG6-OH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126918/
Clinical Information
No Development Reported
CAS Number
42607-87-4
Available Sizes
Curated Selection
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