What is the catalog number for HSPA5 Antibody?

The catalog number for HSPA5 Antibody is OAED00189-50UG.

What sizes are available for HSPA5 Antibody?

HSPA5 Antibody is available in the following size(s): 50 µg.

Is HSPA5 Antibody in stock?

HSPA5 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

HSPA5 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Heat shock protein family A (Hsp70) member 5

Gene Aliases

78 kDa glucose-regulated protein; binding-immunoglobulin protein; BIP; endoplasmic reticulum chaperone BiP; GRP 78; GRP78; GRP-78; heat shock 70 kDa protein 5; heat shock 70kD protein 5; heat shock 70kDa protein 5 (glucose-regulated protein) ; heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A member 5; HSP70 family protein 5; immunoglobulin heavy chain-binding protein; steroidogenesis-activator polypeptide.

Gene ID

25617

Accession Number

NP_005338.1

Reactivity

Immunogen

Synthetic peptide corresponding to the sequence near the C-terminus of rat Grp78 (BiP) . The sequence is completely conserved in mouse and hamster.

Target

Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity) . Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity) . Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) . In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to disrupt the dimerization of ERN1/IRE1, thereby inactivating ERN1/IRE1. Accumulation of misfolded protein in the endoplasmic reticulum causes release of HSPA5/BiP from ERN1/IRE1, allowing homodimerization and subsequent activation of ERN1/IRE1 (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Western blot

Purification

Protein A affinity purified.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol