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TNFRSF1A Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Tumor necrosis factor receptor superfamily, member 1a

Gene Aliases

CD120; CD120a; FPF; p5; p55; p55-R; p60; TN; Tnf; TNF-; TNF receptor alpha chain; TNF-a; TNFal; TNFalpha-R1; TNF-alphaR1; TNF-alpha-R1; TNFAR; TNFR; TNF-R; Tnfr1; TNF-R1; Tnfr-2; TNF-R55; TNFR60; TNFRI; TNFR-I; TNF-RI; TNF-R-I; TNFRp55; tumor necrosis factor receptor 1; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor type I.

Gene ID

21937

Accession Number

NP_001056.1

Reactivity

Bovine|Dog|Drosophila|Hamster|Human|Monkey|Mouse|Porcine|Rabbit|Rat|Sheep|Xenopus|Yeast

Immunogen

Synthetic peptide corresponding to a portion of mouse TNF-R1. The sequence is completely conserved in rat and human.

Target

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunoprecipitation|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Reconstitution

Long Term Storage : //-20C

Specificity

Recognizes human, mouse, rat, bovine, dog, Drosophila, hamster, monkey, pig, rabbit, sheep, Xenopus and yeast TNF-R1. Detects a band of 55kDa by Western blot.

NCBI Gene Symbol

Tnfrsf1a

Host or Source

Rabbit

Protein Name

Tumor necrosis factor receptor superfamily member 1A

Gene Name URL

Tnfrsf1a

Nucleotide Accession Number

NM_001065.3

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