YS 035 (hydrochloride)

YS 035 hydrochloride is a Ca2+ antagonist on cellular uptake and mitochondrial efflux of calcium ions. YS 035 hydrochloride inhibits Ca2+ uptake by muscle cells and inhibits Na+/Ca2+ exchange (Ki=28 µM) . YS 035 hydrochloride is a useful tool for research on the mitochondrial Ca2+ transport[1].

Product Specifications

CAS Number

[89805-39-0]

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ys-035-hydrochloride.html

Purity

99.15

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic)

Smiles

CN(CCC1=CC=C(OC)C(OC)=C1)CCC2=CC=C(OC)C(OC)=C2.[H]Cl

Molecular Formula

C21H30ClNO4

Molecular Weight

395.92

References & Citations

[1]R Deana, et al. Properties of a new calcium ion antagonist on cellular uptake and mitochondrial efflux of calcium ions. Biochem J. 1984 Mar 15;218 (3) :899-905.