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Histone H2A Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Histone cluster 1, H2ae

Gene Aliases

H2A.1, H2A.2, H2A/a, H2AC4, H2AFA, HIST1H2AE

Gene ID

3012; 317772; 8335; 8338

Accession Number

NP_003509.1

Reactivity

Human

Target

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

CHIP, DB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.46 mg/mL

Format

Liquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Specificity

Polyclonal antibody raised in rabbit against histone H2B using a KLH-conjugated synthetic peptide containing an unmodified sequence from the C-terminal part of the protein.

NCBI Gene Symbol

HIST1H2AE

Host or Source

Rabbit

Protein Name

Histone H2A type 1-B/E

Gene Name URL

HIST1H2AE

Nucleotide Accession Number

NM_003518.3

Frequently Asked Questions

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