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TNF-alpha Antibody - PE Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Name

Tumor necrosis factor

Gene Aliases

DIF, TNFA, TNFSF2, TNLG1F, TNF-alpha

Gene ID

7124

Accession Number

NP_000585.2

Reactivity

Human

Target

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Clonality

Monoclonal

Clone

B-D9

Conjugation

PE: Phycoerythrin

Type

Monoclonal Antibody

Applications

FC

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

100 tests/1mL

Format

Lyophilized

Buffer

Phosphate-buffered saline with 5% BSA and 0,1% sodium azide

Molecular Weight

26 kDa

Fragment

Mouse IgG1

Specificity

Recognises both natural and recombinant TNF-a

NCBI Gene Symbol

TNF-alpha

Host or Source

Mouse

Protein Name

Tumor necrosis factor

Gene Name URL

TNF-alpha

Nucleotide Accession Number

NM_000594.3

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