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TNF-alpha Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Tumor necrosis factor

Gene Aliases

DIF, TNFA, TNFSF2, TNLG1F, TNF-alpha

Gene ID

7124

Accession Number

NP_000585.2

Reactivity

Human

Target

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Clonality

Monoclonal

Clone

B-F7

Type

Monoclonal Antibody

Purification

Affinity chromatography & Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/uL

Format

Lyophilized

Buffer

Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

Reconstitution

Stable at +2-8C for 12 months. For longer storage, freeze aliquots.

Molecular Weight

26 kDa

Fragment

Mouse IgG1 Kappa light chain

Specificity

Recognises both natural and recombinant human TNF-a

NCBI Gene Symbol

TNF-alpha

Host or Source

Mouse

Protein Name

Tumor necrosis factor

Gene Name URL

TNF-alpha

Nucleotide Accession Number

NM_000594.3

Frequently Asked Questions

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