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IL-7 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 7

Gene Aliases

IL-7

Gene ID

3574

Accession Number

NP_000871.1

Reactivity

Human

Target

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V (D) J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Clonality

Monoclonal

Clone

B-N18

Type

Monoclonal Antibody

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Bioactivity

This Antibody can be used as Capture in a human IL-7 sandwich Immunoassay to detect human IL-7 in combination with biotinylated human IL-7 Detection Antibody

Format

Lyophilized

Reconstitution

Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C

Molecular Weight

20 kDa

Fragment

Mouse IgG1

Specificity

Recognises both natural and recombinant IL-7

NCBI Gene Symbol

IL-7

Host or Source

Mouse

Protein Name

Interleukin-7

Gene Name URL

IL-7

Nucleotide Accession Number

NM_000880.3

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