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IL-6 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 6

Gene Aliases

CDF, HGF, HSF, BSF2, IL-6, BSF-2, IFNB2, IFN-beta-2

Gene ID

3569

Accession Number

NP_000591.1

Reactivity

Human

Target

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.

Clonality

Monoclonal

Clone

B-E8

Type

Monoclonal Antibody

Applications

BL, FC

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/uL

Format

Lyophilized

Buffer

Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

Reconstitution

Store at +2-8C for 12 months. For longer storage, freeze aliquots

Molecular Weight

24 kDa

Fragment

Mouse IgG1

Specificity

Recognises both natural and recombinant human IL-6

NCBI Gene Symbol

IL-6

Host or Source

Mouse

Protein Name

Interleukin-6

Gene Name URL

IL-6

Nucleotide Accession Number

NM_000600.4

Frequently Asked Questions

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