IL-4 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 4
Gene Aliases
BSF1, IL-4, BCGF1, BSF-1, BCGF-1
Gene ID
3565
Accession Number
NP_000580.1
Reactivity
Human
Target
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Clonality
Monoclonal
Clone
B-G28
Type
Monoclonal Antibody
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.1 mg/ml
Bioactivity
This Antibody can be used as Detection in a human IL-4 sandwich Immunoassay to detect human IL-4 in combination with human IL-4 Capture Antibody
Format
Lyophilized
Buffer
Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*
Reconstitution
Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C
Molecular Weight
17 kDa
Fragment
Mouse IgG1
Specificity
Recognises both natural and recombinant IL-4
NCBI Gene Symbol
IL-4
Host or Source
Mouse
Protein Name
Interleukin-4
Gene Name URL
IL-4
Nucleotide Accession Number
NM_000589.3
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