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IL-4 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 4

Gene Aliases

BSF1, IL-4, BCGF1, BSF-1, BCGF-1

Gene ID

3565

Accession Number

NP_000580.1

Reactivity

Human

Target

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Clonality

Monoclonal

Clone

B-S4

Type

Monoclonal Antibody

Applications

BL

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/uL

Bioactivity

Blocks IL-4 induced proliferation on TF1 cells

Format

Lyophilized

Buffer

Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

Reconstitution

Store at +2-8C for 12 months. For longer storage, freeze aliquots

Molecular Weight

17 kDa

Fragment

Mouse IgG1

Specificity

Recognises both natural and recombinant human IL-4

NCBI Gene Symbol

IL-4

Host or Source

Mouse

Protein Name

Interleukin-4

Gene Name URL

IL-4

Nucleotide Accession Number

NM_000589.3

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