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IL-27 Antibody - PE Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 27

Gene Aliases

P28, IL30, IL-27, IL27A, IL-27A, IL27p28

Gene ID

246778

Accession Number

NP_663634.2

Reactivity

Human

Target

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A) . It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR) .

Clonality

Monoclonal

Clone

B-G49

Conjugation

PE: Phycoerythrin

Type

Monoclonal Antibody

Applications

FC

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

100 tests/1mL

Format

Lyophilized

Buffer

Phosphate-buffered saline with 5 % BSA and 0.1 % sodium azide

Reconstitution

Reconstitute with 1mL of deionized water. Use 10uL to label 106 cells or 100uL of whole blood. Stable at +2-8C for 6 months after reconstitution. DO NOT FREEZE

Molecular Weight

27 kDa

Fragment

Mouse IgG2a

Specificity

Recognizes both natural and recombinant IL-27

NCBI Gene Symbol

IL-27

Host or Source

Mouse

Protein Name

Interleukin-27 subunit alpha

Gene Name URL

IL-27

Nucleotide Accession Number

NM_145659.3

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