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IL-27 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 27

Gene Aliases

P28, IL30, IL-27, IL27A, IL-27A, IL27p28

Gene ID

246778

Accession Number

NP_663634.2

Reactivity

Human

Target

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A) . It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR) .

Clonality

Monoclonal

Clone

B-G44

Type

Monoclonal Antibody

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Bioactivity

This Antibody can be used as Capture in a human IL-27 sandwich Immunoassay to detect human IL-27 in combination with biotinylated human IL-27 Detection Antibody

Format

Lyophilized

Reconstitution

Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C

Molecular Weight

27 kDa

Fragment

Mouse IgG1

Specificity

Recognises both natural and recombinant IL-27

NCBI Gene Symbol

IL-27

Host or Source

Mouse

Protein Name

Interleukin-27 subunit alpha

Gene Name URL

IL-27

Nucleotide Accession Number

NM_145659.3

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