IL-24 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 24
Gene Aliases
C49A, FISP, MDA7, MOB5, ST16, IL10B
Gene ID
11009
Accession Number
NP_001172085.1
Reactivity
Human
Immunogen
Recombinant human IL-24
Target
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Clonality
Monoclonal
Clone
B-C51
Type
Monoclonal Antibody
Applications
ELISA
Purification
Sterile-filtered through 0.22 um.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 ug/uL
Bioactivity
Recognises soluble antigen
Format
Liquid// PBS. Carrier and preservative free.
Buffer
Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
Reconstitution
Store at 2-8° C for 12 months. For longer storage, freeze aliquots.
Molecular Weight
24 kDa
Fragment
Mouse IgG2a kappa light chain
Specificity
Recognises both natural and recombinant human IL-24 (interleukin-24) also called MDA-7 or Th2-specific cytokine FISP
NCBI Gene Symbol
IL-24
Host or Source
Mouse
Protein Name
Interleukin-24
Gene Name URL
IL-24
Nucleotide Accession Number
NM_001185156.1
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