IL-23 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 23 subunit alpha

Gene Aliases

P19, SGRF, IL-23, IL-23A, IL23P19

Gene ID

51561

Accession Number

NP_057668.1

Reactivity

Human

Target

This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23) . IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B) . The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG) . In contrast to IL12, which acts mainly on naive CD4 (+) T cells, IL23 preferentially acts on memory CD4 (+) T cells.

Clonality

Monoclonal

Clone

B-F43

Type

Monoclonal Antibody

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.1 mg/ml

Bioactivity

This Antibody can be used as Detection in a human IL-23 sandwich Immunoassay to detect human IL-23 in combination with human IL-23 Capture Antibody

Format

Lyophilized

Buffer

Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*.

Reconstitution

Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C

Molecular Weight

21 kDa

Fragment

Mouse IgG1

Specificity

Recognises both natural and recombinant IL-23, p19 sub-unit

NCBI Gene Symbol

IL-23

Host or Source

Mouse

Protein Name

Interleukin-23 subunit alpha

Gene Name URL

IL-23

Nucleotide Accession Number

NM_016584.2

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