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IL-2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 2

Gene Aliases

IL-2, TCGF, lymphokine

Gene ID

3558

Accession Number

NP_000577.2

Reactivity

Human

Target

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7) . The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Clonality

Monoclonal

Clone

B-G5

Type

Monoclonal Antibody

Applications

BL, FC, WB

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/uL

Bioactivity

Blocks IL-2 induced proliferation on CTL-L2 murine cell line

Format

Lyophilized

Buffer

Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

Reconstitution

Store at +2-8C for 12 months. DO NOT FREEZE

Molecular Weight

18 kDa

Fragment

Mouse IgG1

Specificity

Recognises both natural and recombinant human IL-2

NCBI Gene Symbol

IL-2

Host or Source

Mouse

Protein Name

Interleukin-2

Gene Name URL

IL-2

Nucleotide Accession Number

NM_000586.3

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