IL-1beta Antibody - PE Conjugated
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 1 beta
Gene Aliases
IL-1, IL1F2, IL1beta, IL1-BETA
Gene ID
3553
Accession Number
NP_000567.1
Reactivity
Human
Target
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Clonality
Monoclonal
Clone
B-A15
Conjugation
PE: Phycoerythrin
Type
Monoclonal Antibody
Applications
FC
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
100 tests/1mL
Format
Lyophilized
Buffer
Phosphate-buffered saline with 1 % BSA and 0.1 % sodium azide
Reconstitution
Reconstitute with 1mL of deionized water. It is recommended to establish the optimal dilution according to the system being used. Use 10 uL of antibody to label 5.105 cells. Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Molecular Weight
31 kDa
Fragment
Mouse IgG1
Specificity
Recognises natural and recombinant human IL-1b
NCBI Gene Symbol
IL-1beta
Host or Source
Mouse
Protein Name
Interleukin-1 beta
Gene Name URL
IL-1beta
Nucleotide Accession Number
NM_000576.2
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