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IL-17A Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 17A

Gene Aliases

IL17, CTLA8, IL-17, CTLA-8, IL-17A

Gene ID

3605

Accession Number

NP_002181.1

Reactivity

Human

Target

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Clonality

Monoclonal

Clone

B-A50

Type

Monoclonal Antibody

Applications

FC

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 tests/2mL

Format

Lyophilized

Buffer

Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide

Reconstitution

Stable at +2-8C for 12 months. For longer storage freeze aliquots.

Molecular Weight

18 kDa

Fragment

Mouse IgG2b

Specificity

Recognizes both natural and recombinant IL-17A

NCBI Gene Symbol

IL-17A

Host or Source

Mouse

Protein Name

Interleukin-17A

Gene Name URL

IL-17A

Nucleotide Accession Number

NM_002190.2

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