IL-17A Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 17A
Gene Aliases
IL17, CTLA8, IL-17, CTLA-8, IL-17A
Gene ID
3605
Accession Number
NP_002181.1
Reactivity
Human
Target
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Clonality
Monoclonal
Clone
B-B51
Type
Monoclonal Antibody
Applications
NT
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 ug/uL
Bioactivity
Neutralises the bioactivity of IL-17A on keratinocytes cell line HaCaT
Format
Lyophilized
Buffer
Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Reconstitution
Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Molecular Weight
18 kDa
Fragment
Mouse IgG2b
Specificity
Recognizes both recombinant and natural human IL-17A
NCBI Gene Symbol
IL-17A
Host or Source
Mouse
Protein Name
Interleukin-17A
Gene Name URL
IL-17A
Nucleotide Accession Number
NM_002190.2
Curated Selection
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