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IL-13 Antibody

Product Specifications

Gene Name

Interleukin 13

Gene Aliases

P600, IL-13

Gene ID

3596

Accession Number

NP_002179.2

Reactivity

Human

Target

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Clonality

Monoclonal

Clone

B-P6

Type

Monoclonal Antibody

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.1 mg/ml

Bioactivity

This Antibody can be used as Detection in a human IL-13 sandwich Immunoassay to detect human IL-13 in combination with human IL-13 Capture Antibody

Format

Lyophilized

Buffer

Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*.

Reconstitution

Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C

Molecular Weight

16 kDa

Fragment

Mouse IgG1

Specificity

Recognises both natural and recombinant IL-13

NCBI Gene Symbol

IL-13

Host or Source

Mouse

Protein Name

Interleukin-13

Gene Name URL

IL-13

CAS Number

9007-83-4

Nucleotide Accession Number

NM_002188.2

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