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IL-13 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 13

Gene Aliases

P600, IL-13

Gene ID

3596

Accession Number

NP_002179.2

Reactivity

Human

Target

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Clonality

Monoclonal

Clone

B-P6

Type

Monoclonal Antibody

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/uL

Format

Lyophilized

Buffer

Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

Reconstitution

Store at +2-8C for 12 months. For longer storage, freeze aliquots

Molecular Weight

16 kDa

Fragment

Mouse IgG1 Kappa light chain

Specificity

Recognises both natural and recombinant human IL-13

NCBI Gene Symbol

IL-13

Host or Source

Mouse

Protein Name

Interleukin-13

Gene Name URL

IL-13

Nucleotide Accession Number

NM_002188.2

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