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IL-12 p35 + p70 Antibody - FITC Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 12A

Gene Aliases

P35, CLMF, NFSK, NKSF1, IL-12A

Gene ID

3592

Accession Number

NP_000873.2

Reactivity

Human

Target

This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN) -gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.

Clonality

Monoclonal

Clone

B-T21

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Monoclonal Antibody

Applications

FC

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

100 ug/ml

Format

Lyophilized

Buffer

Phosphate-buffered saline with 5 % BSA and 0.1 % sodium azide

Reconstitution

Stable at +2-8C for 12 months. For longer storage, freeze aliquots

Molecular Weight

25 kDa

Fragment

Mouse IgG1

Specificity

Recognises natural and recombinant human IL-12 p35 + p70

NCBI Gene Symbol

IL-12

Host or Source

Mouse

Protein Name

Interleukin-12 subunit alpha

Gene Name URL

IL-12

Nucleotide Accession Number

NM_000882.3

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