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CD8 Antibody - PE Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Name

CD8a molecule

Gene Aliases

CD8, p32, Leu2

Gene ID

925

Accession Number

NP_001139345.1

Reactivity

Human

Target

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

Clonality

Monoclonal

Clone

B-Z31

Conjugation

PE: Phycoerythrin

Type

Monoclonal Antibody

Applications

FC

Purification

Affinity chromatography on Protein A

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

100 tests/1mL

Format

Liquid

Buffer

Phosphate-buffered saline with 5% BSA and 0.1% sodium azide

Molecular Weight

26 kDa

Fragment

Mouse IgG2a

Specificity

Recognises the T cell coreceptor, a 32-34 kDa protein

NCBI Gene Symbol

CD8

Host or Source

Human

Protein Name

T-cell surface glycoprotein CD8 alpha chain

Gene Name URL

CD8

Nucleotide Accession Number

NM_001145873.1

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