CD62P Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Selectin P

Gene Aliases

CD62, GRMP, PSEL, CD62P, GMP140, LECAM3, PADGEM

Gene ID

6403

Accession Number

NP_002996.2

Reactivity

Human

Target

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

Clonality

Monoclonal

Clone

B-F46

Type

Monoclonal Antibody

Applications

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 tests/2mL

Format

Liquid

Buffer

Phosphate buffered saline with 1% BSA and 0.09% sodium azide

Reconstitution

Store at +2-8C for 12 months. For longer storage freeze aliquots.

Molecular Weight

91 kDa

Fragment

Mouse IgG1 Kappa light chain

Specificity

Recognizes CD62P, a 140 kDa single chain type I transmembrane glycoprotein present in secretory Î±-granules in platelets, Weibel-Palade bodies in endothelial cells & megakaryocytes.