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CD44 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

CD44 molecule (Indian blood group)

Gene Aliases

IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III

Gene ID

960

Accession Number

NP_000601.3

Reactivity

Human

Target

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Clonality

Monoclonal

Clone

B-R8

Type

Monoclonal Antibody

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/uL

Bioactivity

Suitable for ELISA

Format

Liquid

Buffer

Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

Reconstitution

Stable at +2-8C for 12 months. For longer storage, freeze aliquots

Molecular Weight

82 kDa

Fragment

Mouse IgG1 Kappa light chain

Specificity

Recognises the Hyaluronate Cell Adhesion Molecule (H-CAM), a 85-250 kDa protein

NCBI Gene Symbol

CD44

Host or Source

Human

Protein Name

CD44 antigen

Gene Name URL

CD44

Nucleotide Accession Number

NM_000610.3

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