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CD3 Antibody - FITC Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Name

CD3d molecule

Gene Aliases

T3D, IMD19, CD3-DELTA

Gene ID

915

Accession Number

NP_000723.1

Reactivity

Human

Target

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK) . Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Clonality

Monoclonal

Clone

B-B11

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Monoclonal Antibody

Applications

FC

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

100 tests/1mL

Format

Liquid

Buffer

Phosphate-buffered saline with 5 % BSA and 0.09 % sodium azide

Reconstitution

Stable at +2-8C for 12 months. For longer storage, freeze aliquots

Molecular Weight

19 kDa

Fragment

Mouse IgG1

Specificity

Recognises a 20-32 kDa protein

NCBI Gene Symbol

CD3

Host or Source

Human

Protein Name

T-cell surface glycoprotein CD3 delta chain

Gene Name URL

CD3

Nucleotide Accession Number

NM_000732.4

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