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CD202b Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

TEK receptor tyrosine kinase

Gene Aliases

TIE2, VMCM, GLC3E, TIE-2, VMCM1, CD202B

Gene ID

7010

Accession Number

NP_000450.2

Reactivity

Human

Target

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF) -like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Clonality

Monoclonal

Clone

B-B48

Type

Monoclonal Antibody

Applications

FC

Purification

Ion exchange chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/uL

Format

Lyophilized

Buffer

Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

Reconstitution

Stable at +2-8C for 12 months. For longer storage freeze aliquots.

Molecular Weight

126 kDa

Fragment

IgG1

Specificity

Recognises Tie2, Tek, an unknown KDa protein

NCBI Gene Symbol

CD202b

Host or Source

Mouse

Protein Name

Angiopoietin-1 receptor

Gene Name URL

CD202b

Nucleotide Accession Number

NM_000459.4

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