CD178 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Fas ligand
Gene Aliases
APTL, FASL, CD178, CD95L, ALPS1B, CD95-L, TNFSF6, TNLG1A, APT1LG1
Gene ID
356
Accession Number
NP_000630.1
Reactivity
Human
Target
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE) . Alternatively spliced transcript variants have been described.
Clonality
Monoclonal
Clone
B-R17
Type
Monoclonal Antibody
Applications
FC
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 ug/uL
Bioactivity
Blocks soluble FasL induced apoptosis, Recognises the soluble antigen
Format
Lyophilized
Buffer
Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
Reconstitution
Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Molecular Weight
31 kDa
Fragment
IgG1
Specificity
Recognises APO1L, Fas ligand (FAS L), a 40 kDa protein
NCBI Gene Symbol
CD178
Host or Source
Mouse
Protein Name
Tumor necrosis factor ligand superfamily member 6
Gene Name URL
CD178
Nucleotide Accession Number
NM_000639.2
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