CD126 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 6 receptor
Gene Aliases
IL6Q, gp80, CD126, HIES5, IL-6R, IL6RA, IL6RQ, IL-1Ra, IL-6RA, IL6QTL, IL-6R-1
Gene ID
3570
Accession Number
NP_000556.1
Reactivity
Human
Target
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Clonality
Monoclonal
Clone
B-R6
Type
Monoclonal Antibody
Applications
FC, IP, IHC-F
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 ug/uL
Bioactivity
Blocks IL-6 induced proliferation of XG-1 cells, Inhibits IL-6 binding to its receptor, Recognises soluble and membrane bound IL-6 R
Format
Lyophilized
Buffer
Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Reconstitution
Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Molecular Weight
52 kDa
Fragment
IgG1
Specificity
Recognises the Interleukin-6 Rα subunit, IL-6 Ra, IL-6 R, a 80 kDa protein
NCBI Gene Symbol
CD126
Host or Source
Mouse
Protein Name
Interleukin-6 receptor subunit alpha
Gene Name URL
CD126
Nucleotide Accession Number
NM_000565.3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4643807 1.0 µg DNA
4732471D19Rik sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details 492904 100 µL
SSTR5 (Somatostatin Receptor Type 5, Somatostatin Receptor 5)
Sign In for Pricing
View Details 
![1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido-[1,2-a][1,5]diazocin-8-one](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
FD117142-01 1 g
1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido-[1,2-a][1,5]diazocin-8-one
Sign In for Pricing
View Details FD117142-02 2 g
1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido-[1,2-a][1,5]diazocin-8-one
Sign In for Pricing
View Details FD117142-03 5 g
1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido-[1,2-a][1,5]diazocin-8-one
Sign In for Pricing
View Details