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CD11a Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Integrin subunit alpha L

Gene Aliases

CD11A, LFA-1, LFA1A

Gene ID

3683

Accession Number

NP_001107852.1

Reactivity

Human

Target

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Clonality

Monoclonal

Clone

B-B15

Type

Monoclonal Antibody

Applications

FC

Purification

Affinity chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/uL

Format

Lyophilized

Buffer

Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

Reconstitution

Stable at +2-8C for 12 months. For longer storage, freeze aliquots

Molecular Weight

129 kDa

Fragment

IgG1

Specificity

Recognises the αL integrin of LFA-1 complex, a 180 kDa protein

NCBI Gene Symbol

CD11a

Host or Source

Mouse

Protein Name

Integrin alpha-L

Gene Name URL

CD11a

Nucleotide Accession Number

NM_001114380.1

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