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VTCN1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

V-set domain containing T cell activation inhibitor 1

Gene Aliases

B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7S1; B7X; immune costimulatory protein B7-H4; PRO1291; Protein B7S1; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; VCTN1; V-set domain-containing T-cell activation inhibitor 1.

Gene ID

79679

Accession Number

NP_001240778.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Pro153 - Thr241

Target

Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.65 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

10 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against VTCN1. It has been selected for its ability to recognize VTCN1 in immunohistochemical staining and western blotting.

NCBI Gene Symbol

VTCN1

Host or Source

Rabbit

Protein Name

V-set domain-containing T-cell activation inhibitor 1

Gene Name URL

VTCN1

Nucleotide Accession Number

NM_001253849

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