What is the catalog number for TICAM2 Antibody?

The catalog number for TICAM2 Antibody is OACD07749-100UL.

What sizes are available for TICAM2 Antibody?

TICAM2 Antibody is available in the following size(s): 100 µL.

Is TICAM2 Antibody in stock?

TICAM2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

TICAM2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Toll-like receptor adaptor molecule 2

Gene Aliases

B430113A10; T; TICAM-2; TIR domain-containing adapter molecule 2; TIR domain-containing adapter protein; Tirp; toll/interleukin-1 receptor domain-containing protein; Toll-interleukin I receptor domain (TIR) -containing adaptor molecule (TICAM) 2; TR; TRAM; Trif; TRIF-related adapter molecule; TRIF-related adapter molecule TRAM; TRIF-related adaptor molecule.

Gene ID

225471

Accession Number

NP_775570.1

Reactivity

Mouse

Immunogen

Range: Ser20 - Ser196

Target

Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial. Involved in IL-18 signaling and is proposed to function as a sorting adaptor for MYD88 in IL-18 signaling during adaptive immune response.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

26 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against TICAM2. It has been selected for its ability to recognize TICAM2 in immunohistochemical staining and western blotting.