What is the catalog number for SUMO2 Antibody?

The catalog number for SUMO2 Antibody is OACD07558-1ML.

What sizes are available for SUMO2 Antibody?

SUMO2 Antibody is available in the following size(s): 1 mL.

Is SUMO2 Antibody in stock?

SUMO2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

SUMO2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Small ubiquitin like modifier 2

Gene Aliases

HSMT3; sentrin 2; Sentrin-2; small ubiquitin-related modifier 2; SMT3 homolog 2; SMT3 suppressor of mif two 3 homolog 2; Smt3A; SMT3B; SMT3H2; SUMO3; SUMO-3; ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B.

Gene ID

6613

Accession Number

NP_001005849.1

Reactivity

Human|Mouse|Porcine|Rat

Immunogen

Range: Met1 - Tyr95

Target

Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451 (PubMed:26524494) . This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (PubMed:18408734, PubMed:18538659, PubMed:21965678, PubMed:9556629) . Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

8 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against SUMO2. It has been selected for its ability to recognize SUMO2 in immunohistochemical staining and western blotting.