SRGN Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Serglycin
Gene Aliases
Gp600; mastocytoma proteoglycan core protein; Pr; Prg; Prg1; proteoglycan 1, secretory granule; proteoglycan, secretory granule; secretory granule proteoglycan core protein; serglycin; Sg; Sgc.
Gene ID
19073
Accession Number
NP_035287.1
Reactivity
Mouse
Immunogen
Range: Ala28 - Ile152
Target
Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.63 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
17 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against SRGN. It has been selected for its ability to recognize SRGN in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Srgn
Host or Source
Rabbit
Protein Name
Serglycin
Gene Name URL
Srgn
Nucleotide Accession Number
NM_011157
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
