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SP140 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

SP140 nuclear body protein

Gene Aliases

Lymphoid-restricted homolog of Sp100; lymphoid-specific SP100 homolog; LYSP100; LYSP100-A; LYSP100-B; nuclear autoantigen Sp-140; nuclear body protein SP140; speckled 140 kDa.

Gene ID

11262

Accession Number

NP_001005176.1

Reactivity

Human|Rat

Immunogen

Range: Gly443 - Met655

Target

Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body (PubMed:8910577) . May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection (PubMed:8910577) . May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails (PubMed:24267382) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

20 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against SP140. It has been selected for its ability to recognize SP140 in immunohistochemical staining and western blotting.

NCBI Gene Symbol

SP140

Host or Source

Rabbit

Protein Name

Nuclear body protein SP140

Gene Name URL

SP140

Nucleotide Accession Number

NM_001005176

Frequently Asked Questions

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