SIGLECE Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Sialic acid binding Ig-like lectin E
Gene Aliases
Cd170; MIS; mSigle; mSiglec-E; myeloid inhibitory siglec; sialic acid binding Ig-like lectin 5; sialic acid-binding Ig-like lectin 12; Sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin E; sialic acid-binding Ig-like lectin-like 1; sialic acid-binding immunoglobulin-like lectin E; Sigl; siglec-12; Siglec12; siglec-5; Siglec5; Siglec9; siglec-E; siglec-L1; Siglecl1; SIGLEC-like 1.
Gene ID
83382
Accession Number
NP_112458.2
Reactivity
Mouse
Immunogen
Range: Leu27 - Met141
Target
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
52 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against SIGLEC12. It has been selected for its ability to recognize SIGLEC12 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Siglece
Host or Source
Rabbit
Protein Name
Sialic acid-binding Ig-like lectin 12
Gene Name URL
Siglece
Nucleotide Accession Number
NM_031181
Curated Selection
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