Ingenol disoxate
Ingenol disoxate (LEO 43204) is a drug metabolite, that exhibits potential in ameliorating actinic keratosis[1].
Product Specifications
CAS Number
1383547-60-1
Product Name Alternative
LEO 43204
UNSPSC
12352005
Hazard Statement
H300+H330, H315, H318, H361
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ingenol-disoxate.html
Purity
99.92
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O[C@]([C@H]1OC(C(C(CC)=NO2)=C2CC)=O)([C@@H](C(CO)=C[C@@]3([H])[C@H](C4(C)C)[C@H]4C5)O)[C@]([C@@H]5C)(C=C1C)C3=O
Molecular Formula
C28H37NO7
Molecular Weight
499.60
Precautions
H300+H330, H315, H318, H361
References & Citations
[1]Weiss J, et al., A seamless phase I/II dose-finding trial assessing ingenol disoxate (LEO 43204) for field treatment of actinic keratosis on the scalp. Br J Dermatol. 2017 Jun;176 (6) :1456-1464.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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